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Drug treatments were added in KRB (25 mM glucose) (1 hr, 37 C, 5% CO 2 )

Although nearly 50 years of published research show that GHK-Cu Copper Tripeptide-1 Powder can increase skin glycosaminoglycan production, inhibit matrix metalloproteinases, and regulate mild inflammatory responses, the existing data has major compliance limitations

Furthermore, there are drug interactions, particularly noted among online communities like Longecity, against the concurrent use of FOXO4-DRI with certain compounds such as Rapamycin, Quercetin, corticosteroids, and cortisol, due to potential interactions that might diminish the peptide's senolytic efficacy