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Transcription factor Egr-1 activates collagen expression in immortalized fibroblasts or fibrosarcoma cells

this channel appears to be positively modulated by intracellular lactate levels, forming a possible feedback loop for rapid lactate efflux [13]

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Consistent with this protective role, we found that mice lacking Fth in cardiomyocytes develop ferroptosis-induced cardiomyopathy

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