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Functional disability was assessed using the Global Assessment of Functioning (GAF) scale

Human Prdx6 displays altered secondary and tertiary structure at acidic pH as compared to neutral pH Impact of change in solution pH on hPrdx6s conformation is probed by using various spectroscopic tools including circular dichroism (CD) and fluorescence spectroscopy (See Fig

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The inhibitory effect of mTORC1 on autophagy is induced by phosphorylating and suppressing the nuclear translocation of transcription factor EB (TFEB) 70

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