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Specific substrate-product pairs are in equilibrium with NAD and NADH in their respective compartments

Ophthalmoplegia refers to paralysis of eye muscles (the -plegia suffix is also used in paraplegic )

Additionally, the substantial consumption of CPR and NADPH leads to impairment of the cellular respiratory chain [32]

However, older adults and those who do not get adequate amounts of this nutrient (2.4 micrograms for adults) from food, such as vegans and vegetarians, are advised to take vitamin B12 supplements