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Sample Preparation DC were infected for 17 hours with PR8 (MOI 5 or 1) followed by lysis, homogenization, and fractionation by centrifugation

Consistently, both antibodies elevated ADPR production in MM cells, with DARA reaching statistical significance (p = 0.03) and ISA showing a near-significant trend (p = 0.07)

Mol Neurobiol 47:632644 Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L, Ragozzino D (2011) Synaptic pruning by microglia is necessary for normal brain development

This multiwavelength approach targets several enzyme sites to stimulate mitochondrial output and modify degenerative processes

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