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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Egorov E., Ropo A., Group T.a.t.S

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Cest dautant plus important que les radicaux libres provoquent la dtrioration des lipides des membranes cellulaires (peroxydation), qui met les cellules en danger et accrot le risque de maladie, ce qui peut entraner la mort des cellules et une probabilit accrue de maladie

Under physiological conditions, the antioxidant system in the body, covering antioxidant enzymes [superoxide dismutase, catalase (CAT), and glutathione (GSH) peroxidase (GPX)] and antioxidants (vitamins C and E, flavonoids, carotenoids, GSH, and micronutrients), is involved in maintaining the dynamic balance between ROS production and metabolism

The most favorable developmental outcomes are associated with early implementation of the ketogenic diet (89) and are most pronounced in individuals with relatively mild presentations of pyruvate dehydrogenase complex deficiency, such as childhood-onset ataxia (73)

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