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Subcutaneous administration of vitamin B12 is sometimes employed, especially in patients with congenital cobalamin metabolism disorders who require high doses to maintain normal metabolic pathways

doi:10.1016/j.clnu.2016.11.011 Tajima A, Kubo Y, Horiguchi S, Shoji K, Kawabata T

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Concurrent medical conditionssuch as Crohn's disease, coeliac disease, or gastric surgerycan impair absorption and delay treatment effects