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The concentration of topical niacinamide skin care products go up to 10%, but according to studies, they are as effective with as low as 2%

For those patients that are allergic, you may not have to bring it down to these extreme low levels

PLoS One 12(11):e0187351 Zmock M, Hofbauer S, Schaffner I, Gasselhuber B, Nicolussi A, Soudi M, Pirker KF, Furtmller PG, Obinger C (2015) Independent evolution of four heme peroxidase superfamilies