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Moreover, polypharmacy, the concurrent use of multiple drugs, increases the risk of drug interactions, which may alter the efficacy of TCM interventions

Other studies have also reported that peritumoral stromal neutrophils and mesenchymal cells secrete high levels of HGF, which drove high rates of proliferation, invasion and metastasis in HCC by promoting the EMT (Ding et al., 2010

The molecule pairs a segment derived from the FOXO4 forkhead/transactivation interface with a poly-arginine cell-penetrating sequence, allowing it to cross cell membranes in experimental systems