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2018 [doi: 10.1111/and.12944][Epub]

Due to their imidazole ring, they possess unique acid-base abilities and under pH 6 are usually in a state of protonation, i.e., being positively charged ( Ka ) of imidazole rings of histidine residues often reflects the overall protein catalysis functions

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In a genetic mouse model, the loss of zinc transporter Zip10 leads to reduced zinc levels in macrophages, triggering p53-dependent apoptosis [74]

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