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Precipitated histones were pelleted at 10,000 x g for 5 minutes, washed once with 0.1% HCl in acetone and twice with acetone followed by centrifugation at 14,000 x g for 5 minutes

[59, 60, 61] In mice of doxorubicin- and angiotensin II (Ang II)-induced heart failure, navitoclax reduced inflammation, cardiac fibrosis and dysfunction

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While cationic polymers like PEI can enhance loading, they introduce well-documented cytotoxicity constraints, forcing an explicit engineering trade-off between delivery potency and biological safety (Shirbaghaee and Bolhassani, 2016)

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Thus, a drone is a key individual at the origin of a cascade of events required for colony growth and sustainability