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The total gradient time was 19 min and went from 8% to 24% acetonitrile (ACN) in 12.5 min, followed by 2.5 min to 36%

However, this strategy is only attractive if the therapeutic agent itself is not a substrate for CPA, or if the case, that its functional activity is not negatively affected by C-terminal cleavage

doi: 10.3892/ol.2020.12137 173

While less extensively researched than BPC-157, the formulation represents an interesting option for those exploring peptides for brain function

Effect of aging on the bloodbrain barrier