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Despite the advancements represented by HDIs databases, significant limitations persist

3,4,5,6,7 Here, we provide a comprehensive update of recent efforts to target ferroptosis for treating a variety of relevant diseases, and we discuss the safety and efficacy of ferroptosis agonists and antagonists, as well as their pharmacokinetics profiles, their experimental stage in the drug discovery process, and opportunities for further clinical development

Billingham, Email: [email protected]

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Zhongguo Zhong Yao Za Zhi 39:777784 Acknowledgements The authors acknowledge the Department of Botany, Interdisciplinary School of Life Sciences (ISLS), Institute of Science, Banaras Hindu University, supported by the Department of Science and Technology, Fund for Improvement of Science and Technology (DST-FIST), and Centre for Advanced Study (CAS), for providing essential laboratory facilities

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