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In muscle tear models, the combination addresses both the inflammatory response and the structural repair phase simultaneously with BPC-157 modulating pro-inflammatory cytokines (TNF-, IL-6) and oxidative stress markers, and TB-500 recruiting progenitor cells and mesenchymal cells to the post-injury site while BPC-157 drives their subsequent differentiation and organisation

We recently found that Nrf2 redirects glucose and glutamine into anabolic pathways and promotes metabolic activities that are advantageous for proliferation (Mitsuishi et al., 2012)

Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells

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Images were acquired using SP8 (Leica) or FV3000 (Olympus) confocal microscope, and were analyzed in Fiji 63 and Adobe Photoshop CC