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Zhang J, Lin Y, Lin Z, Wei Q, Qian J, Ruan R et al

Accessed May 23, 2025

doi: 10.1016/j.molcel.2015.06.011 66 KoppulaPZhangYZhuangLGanB

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High concentrations of GSH also inhibit melanin production, either through direct binding with polyphenol oxidases required for melanin production, or by reduction of radical melanin precursors (e.g., dopaquinone) with the latter leading to formation of thiol-quinone conjugates used in pheomelanogenesis 2527

We always recommend patch-testing the product before applying it widely to an area, and if you see any signs of irritation, stop using it