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Neonatal exposure to a wild-derived microbiome protects mice against diet-induced obesity

The following primary antibodies were used for immunostaining in this study: rabbit anti-GNPT subunit (1:100, homemade), rabbit anti-LYSET (1:100, HPA-48559, Millipore-Sigma), mouse anti-GM130 (1:100, 610822, BD Biosciences), and anti-GCN4 [IPI-C11L34] (1:100, 218104-rAb, Addgene), mouse anti-IL-2Ra (1:100, 05-170, Millipore-Sigma)

Consequently, broad CAF-targeting therapies must be approached with caution, as removing all fibroblasts can inadvertently dampen immune surveillance, whereas targeting the right subtype can alleviate immunosuppression

Moreover, the numerous bioactive compounds found in spirulina have antioxidant potential, neutralizing free radicals and reactive oxygen species, thus reducing oxidative stress and slowing the aging process of the body

doi: 10.1016/j.apsb.2021.03.036 32 KoppulaP.ZhuangL.GanB

Peripheral voltage-gated cation channels in neuropathic paintheir potential as therapeutic targets