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It is the primary neurotransmitter responsible for learning, memory consolidation, and sustained attention

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Interestingly, single nucleotide polymorphisms in the IL-1, IL-6 and IL-10 genes have been associated with cachexia in gastrointestinal cancers ( The identification of these cytokines as central players in cachexia led to the development of therapeutic strategies focusing on their targeting (Monk et al., 2006

Further investigations including echocardiography or other imaging modalities depend on the history and physical examination

1 Introduction Dry Eye Disease (DED) is a complex, chronic ocular surface disease arising from diverse etiologies, significantly impacting quality of life (Figure 1) (Liu et al., 2022

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