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If amla, citrus, and leafy greens rarely make it onto your plate, your baseline vitamin C and by extension, your glutathione recycling may already be running low

H 2 S is mainly generated by three endogenous enzymes with different organ/tissue distributions, all of which are related to cysteine metabolism: the trans-sulphuration pathway pyridoxal-5-phosphate-dependent-CBS and CSE, and 3-MST

Integrating ChIP-seq, HiC, and PRO-seq datasets, we revealed broad functional binding of NRF2 at enhancer elements, including NRF2-dependent enhancer-derived RNA (eRNA) synthesis and extensive linkages between NRF2 target promoters and enhancers

Maintaining sufficient glutathione stores protects hepatocytes from oxidative stress and supports efficient detoxification

455 Sulforaphane 503 and dexmedetomidine 505 both inhibit ferroptosis by activating the Nrf2 pathway to improve diabetic cardiomyopathy

Stem Cells 30, 372378