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Combining garlic extract with gemcitabine enhanced the chemotherapy cytotoxic effect on breast cancer cells (45), suggesting a potential role for garlic or its bioactive compounds in the management of gemcitabine resistant pancreatic cancer

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At the critical metabolic node, the electron transferring flavoprotein/butyryl-CoA dehydrogenase (EtfAB/Bcd) complex catalyzes the reduction of crotonyl-CoA to butyryl-CoA, from which butyrate is generated subsequently through two distinct enzymatic routes

The Myc-Pds5B construct was kindly provided by Dr