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Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways

To improve the pharmacological properties and enable tumor-selectivity, the phenylazopyridine ligand was terminally functionalized with a hydroxy group that could be used for further chemical modifications

doi: 10.1186/s40425-018-0340-z 228 AhmedNRatnayakeMSavoldoBPerlakyLDottiGWelsWSet al

This provides Glyteine with the capacity to increase cellular glutathione levels above homeostasis

It also helps improve fat metabolism, treat autism and also avoid cancer

To address this, we employed a sequential, multi-omics bioinformatics workflow to generate a testable mechanistic hypothesis, followed by rigorous experimental validation