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Research found that Tunicamycin administration increased the Prevotellaceae to Erysipelotrichaceae ratio in the GM of liver-injured mice, a trend reversed by Berberine treatment

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Among these agents, sotorasib (AMG 510) and adagrasib (MRTX849) have emerged as promising therapeutic options, demonstrating notable clinical efficacy in patients with KRAS G12C-mutant NSCLC (85,94)