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Then, we change the dose and how often they get it based on test results and how theyre doing

doi: 10.1200/jco.20.03433 215 McKayRRDe VelascoGWernerLBellmuntJHarshmanLSweeneyCet al

that is, when pharmacokinetics are linear. In this situation, when the drug is eliminated (ie, metabolized and excreted from the body), the fall in blood level is proportionate to the concentration of the drug in blood