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This guide explains how IGF-1 LR3 works, what current science suggests, and why medical supervision is essential before considering peptide-based therapies

Layfield R, Lowe J, Bedford L

It can change various mitochondrial-related functions, including increasing the production of mitochondrial ROS, reducing mitochondrial transmembrane potential, and changing mitochondrial calcium homeostasis ( in vivo and in vitro through c-Raf and MEK (Figure 5) (Schaedler et al., 2010)