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Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review

Askarizadeh A, Mashreghi M, Mirhadi E, Mirzavi F, Shargh VH, Badiee A, et al

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Hence, our data suggests that only a very short pre-treatment of erastin suffices to synergize with cisplatin to efficiently induce cancer cell death, findings that might guide us in the design of novel cancer treatment paradigms

This spatial metabolic heterogeneity confers marked differences in therapeutic responsiveness among cancer cells residing in distinct tumor niches

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