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Neural Correlates of the Cortisol Awakening Response in Humans

118 E2 has been demonstrated in numerous studies to alter systems involved in the pathophysiology of depression, including the serotonin and norepinephrine systems, and to considerably alleviate depressive symptoms in animal models

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Although TVEAE produced some histopathological changes in the liver and kidney, it was still less toxic than the positive control drug (Fig

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