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For experiments, Apoe -/- mice were fed a high cholesterol diet (HCD, 21.2% fat by weight and 0.2% cholesterol, TD.88137, Envigo, Indianapolis, IN, USA) for a total period of eight weeks

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Trans-membrane electron transfer systems using ascorbate or NADH as electron donors serve to reduce semidehydroascorbate present in secretory vesicles and in the extracellular space [26, 31]

Likewise, zinc oxide nanoparticles (ZnONPs) at doses higher than 50 mg/kg were found to induce oxidative stress in the testes of diabetic rats (251)

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