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2006), and transcription factors involving nuclear factor NF-B

In this case, KAR 1 might need to be converted into an active form in vivo for signal transduction to occur (Supplementary Fig

The accepted mechanism of this catalytic reaction (derived from many years of biochemical and modelling studies) envisages a two-step process shown in Equations 2 and 3 [Alfonso-Prieto, 2008]