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doi: 10.3390/nu3100858 60 LinMYde ZoeteMRvan PuttenJPStrijbisK
In vivo and in vitro experiments have shown that a lack of glutathione can lead to mitochondrial damage and cell death caused by an increase in toxic oxygen forms, leading to an increase in free radicals
In blood pressure studies, the peptide did not affect basal blood pressure but counteracted both L-NAME-induced hypertension and L-arginine-induced hypotension
This suggests that SapM may have a pleiotropic role with a wider importance on Mtb infection than initially thought
[4] Lewis DD, Villarreal FD, Wu F, Tan C