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Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo

The apoptosis is efficiently inhibited by the anti-apoptotic Bcl-2 gene product, which has been shown to exert an antioxidant function

doi: 10.1007/s11738-021-03281-7 206 ZhangM.AnP.LiH.WangX.ZhouJ.DongP.et al

It is a constituent of the inner mitochondrial membrane and has many fundamental functions, including acetyl CoA uptake [20], improving mitochondrial bioenergetics [21] and prevention of mitochondrial enzyme oxidation [22]

Vitamin C helps preserve lung tissue by scavenging free radicals, lowering oxidative stress, and moderating the inflammatory response

It can reverse damage already done, at least in rats