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3.3.3 Altered fatty acid metabolism affecting follicular growth HFD disrupts ovarian fatty acid metabolism by upregulating fatty acid uptake and trafficking (increased CD36, FABP expression), impairing -oxidation (reduced PPAR targets, CPT1, ACOX), and promoting lipid storage via PPAR-mediated FSP27/CIDE-C upregulation, leading to ectopic lipid accumulation, lipotoxicity, and oxidative stress compromising folliculogenesis at multiple stages (Yan et al., 2020

And some of the brides have genuinely seen some improvement in skin like clarity, brightness, within just a few weeks, only because of following it on a regular basis and making themselves properly consistent

Microbiology (Open Oregon State University, 2019)

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