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Probiotic strains, such as Lactobacillus and Bifidobacterium, have been shown to reduce intestinal permeability and modulate systemic inflammation (Corridoni et al., 2012)

297 However, overexpression of PINK1 inhibit the mtDNA-cGAS-STING pathway, so impaired mitophagy boosts inflammatory responses by promoting mtDNA DAMPs in aging

Kolaek S, Hojsak I, Berni Canani R et al (2017) Commercial probiotic products: a call for improved quality control

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