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Traditionally, stem-like cells are defined by their capacity to initiate tumors in experimental models, but this property is not always exclusive to them, given that similar behaviors may also be seen in persister cells or in cells exposed to SASP signaling

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doi: 10.1016/j.toxlet.2021.05.010 140 LanC-CSuW-LYangM-Cet al

doi: 10.1093/EURHEARTJ/EHAC031 233 AhamedJLaurenceJ

The modifications that make flmodafinil and fladrafinil more potent than the parent compound also introduce unknown variables regarding their effects on the cardiovascular system, neurological function, and potential for dependence

The nal selection among these approaches will often depend on the type of ligand being immobilized, the support desired for this ligand, and the conditions that can be tolerated by both the ligand and support during the immobilization process