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Somatodendritic expression of JAM2 inhibits oligodendrocyte myelination

This study also importantly demonstrates that metformin treatment significantly alters the metabolic profile and inflammatory secretome in rectal cancer biopsies, with minimal impact on non-cancer rectal tissue, supporting its potential as a radiosensitising agent in rectal cancer

These amino acids are absorbed and serve as building blocks for endogenous glutathione synthesis in body cells

Some face stricter controls

The delay between glutathiones discovery in 1888 and its clinical use in the 1980s stems from three factors: poor oral bioavailability (the tripeptide was degraded in the gut before absorption), lack of understanding of its antioxidant mechanism until glutathione peroxidase was discovered in 1957, and institutional medicines slow adoption of redox biology as a treatment framework

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease