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Description

A.SaadK.et al (2018)

A.YeD.KazaA.et al (2012)

Systemic Distribution Subcutaneous injection delivers the full dose into circulation

Extensive workup was unrevealing for possible infective, inflammatory or endocrine causes except for vitamin B 12 deficiency

Its structure resists degradation, supporting longer laboratory procedures

Antagonist autoAb directed against MMP1 and MMP3 were described to block the enzymatic activity of these proteins, thus reducing the digestion of matrix [161, 162]