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This reaction requires the NADPH generated by glucose-6-phosphate dehydrogenase (G6PD), the first enzymatic reaction of the HMP shunt

Despite promising regenerative outcomes in animal modelssuch as achieving NP cell survival rates reaching 85%, a 3.3-fold increase in COL2 synthesis, and 87% recovery of disc height through spatiotemporally controlled release, ROS scavenging, and immune modulationsignificant challenges remain for clinical translation

Consequently, along with the filament classes, we observed 2D averages of this construct that represented these degradation products (Supplementary Fig

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Herein, to determine whether CHCHD2 knockout affects GBM cell invasion, a bead invasion assay in GelMA hydrogels (Young's modulus 2.90.45 kPa) was used as a three-dimensional culture platform to model biophysical aspects of the brain parenchyma and GBM cell invasion (33,34)