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Patients with vegan diets, post-bariatric history, or absorption challenges who need consistent repletion

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Why does one person need monthly shots for life, while another might only need a short course

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For patients with pernicious anaemia or severe malabsorption , oral supplementation with either form is usually insufficient

NICE NG28 similarly recommends considering periodic monitoring of B12 in people at risk on long-term metformin this is not a blanket recommendation for all metformin users, but is targeted at those with relevant risk factors or symptoms