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Medical Therapy First-Tier Drugs: VMAT2 Inhibitors (Table 3) Mechanism VMAT2 is a key vesicular protein that traverses the membrane and is involved in recycling dopamine, norepinephrine, and serotonin after their reuptake into the neuron from the synaptic cleft

CircAKT3 promotes cell proliferation, survival and glutamine metabolism of gastric cancer by activating SLC1A5 expression via targeting miR-515-5p

459,460,461,462 ROS help transport the FOXO transcription factor into the nucleus through phosphorylation by JNK or MST1

Excess iron can drive oxidative stress , essentially creating internal "rust", which damages cells, contributes to inflammation, and ironically impairs detoxification

Its primary job is to tackle the threat of free radicals

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