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Since the data met the assumptions of normality and homogeneity of variance, inter-group comparisons were conducted using one-way ANOVA followed by Tukeys multiple comparisons test

191 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU, also known as carmustine) is a selective glutathione disulfide reductase (GSR) inhibitor 192 and is used as a chemotherapy drug for treating brain cancer and lymphoma

Most other CB-839 in vitro studies have focused on CB-839s pharmacological interactions and uses in combination therapy rather than its use as a single agent