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10.1371/journal.pone.0023660 PLoS ONE 123 TrinhJ.FarrerM

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Posttranslational modifications of ROS-mediated kinase activity most probably contribute to the diversity and intensity of gene expression following microbial activation of innate immunity (Kolls, 2006)

This mechanistic distinction suggests the two agents could be synergistic rather than redundant, though that hypothesis has not been tested in a published clinical trial as of January 2025

Palmer, M., Paris Perez, J., Tarver, J., Cawthorne, T., Frayne, M., Webb, S., Baker, E., Yorke, I., Hay, D., Slonims, V., Pickles, A., Simonoff, E., Scott, S., and Charman, T., Journal of Autism and Developmental Disorders , 2021, vol