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Key Takeaways: GSH depletion in Type 2 Diabetes is driven by impaired synthesis, not just increased oxidative consumption

As they are highly reactive, ROS can react with and damage important molecules, such as DNA , lipids (such as those in cell membranes) and proteins (including key enzymes and structural proteins)

Half life is ~50 min Major drug Interactions: MAOI inhibitors would be expected to increase cocaine's effects & toxicity

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10.1006/abbi.1994.1105 Arch

MTHFR has two forms, heterozygous or homozygous