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Oxidative stress, another consequence of inflammation, may also contribute 91

67,68,69 The proportion of the CD14 + CD16 + subset of monocytes was elevated with downregulated expression of CX3CR1 and HLA-DRA during aging, whereas the CD14 + CD16 - subset was decreased

432 Epidemiological studies suggest that maintaining a serum uric acid level below 5.5 mg/dl may offer enhanced cardiovascular and renal protection compared to target levels of 6 mg/dl or higher

Statistical analyses were done in R (version 4.1.1)

Briefly, 40 g of proteins were transferred onto a Nanosep 10-kDa-cutoff filter (Pall Corporation, Portage, MI, United States) previously rinsed with 100 L of 1% (v/v) formic acid (FA), the filter was washed two times with 200 L urea buffer (8 M urea and 100 mM Tris, pH 8.5 in Milli-Q water) to remove the detergents present in the extraction buffer

fetal bovine serum (FBS;Thermo Fisher Scientific)