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Biol Trace Elem Res 157(2):156163

10.1021/acs.jproteome.6b00638 44 KimuraT.JiaJ.KumarS.ChoiS

2026 Feb 2

Head-to-head trials versus conventional treatments

Nitric oxide signaling connects the three systems, regulating blood flow and inflammatory responses across muscular, digestive, and neural tissue simultaneously

16,51,52 Herniated discs trigger an innate and adaptive immune response with infiltration of macrophages, T and B cells, and the up-regulation of a myriad of pro-inflammatory cytokines, e.g., IL-1, IL-6, IL-8, IL-10, IL-17, IFN-, CCL2, TNF- and PGE2