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However, clinical translation still faces challenges, such as administration routes, dosage optimization, and toxicity assessment, which require further investigation

In the following, we will introduce the utilization of peptides to modulate the functions of these cells, thereby improving the immunosuppression within the TME of PCa Figure 1

This study pioneered an in vivo self-assembly strategy to develop a PKM2 allosteric converter, dually suppressing the Warburg effect and chemoresistance in renal cell carcinoma (RCC) through an enzyme-responsive self-assembly and sustained activation mechanism

Another eastern immigrant was John C

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