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Chem Biol Interact 205(1):5362

The high level of GSH in root nodules and the presence of an active ascorbate-glutathione (AsA-GSH) cycle suggest that GSH participates in the protection of the nitrogen-fixing process against reactive oxygen species (ROS) resulting from the active nodule metabolism

Acne usually develops due to a combination of factors, including: Excess sebum (oil) production Clogged hair follicles Growth of acne-causing bacteria Hormonal fluctuations Inflammation Genetic predisposition Since glutathione does not directly influence these main causes, it is unlikely to be responsible for acne in most people