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doi:10.1152/japplphysiol.00945.2010 Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P

All this information that is being generated on the molecular and pharmacodynamic mechanisms leads us to see the need to create multidisciplinary investigative groups for the development of hepatoprotectors or hepatic antioxidants

These parameters cannot be directly translated to human dosing, as appropriate scaling based on joint volume, body weight, and pharmacokinetics would be required