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Conclusion Considering the promising effects of vitamin B12 in improving disease severity and anxiety of FM patients as well as the absence of any side effects in the studied dosage, we postulate that vitamin B12 has a strong potential to consider, at least, as an adjunctive therapy of FM

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In addition, section S0 (Non-approved substances) includes substances used for doping which are not included in other sections of the Prohibited List that are not approved by any governmental regulatory health authority for human therapeutic use

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In SPMS, characterized by steady deterioration without acute attacks, treatment strategies often involve continuing or altering DMT used during the earlier RRMS phase, such as interferon beta, or considering immune-modulating agents, such as methotrexate, cyclophosphamide, or glucocorticoid pulses [142, 143]