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Neurological damage: Promote neuroprotection and helps in recovery from neurological impairments

Finally, in BTC, cisplatin-gemcitabine remains the standard first-line therapy, with mOS ranging from 12.6 to 13.5 months and mPFS of 5.57.4 months (NCT02182778) [30]

Zesiewicz et al., 2018)

Additionally, plasmatic Gln measurement in the patients showed that those with lower levels presented a worse outcome (mortality, LOS, and infections) in which a supplementation with higher doses might be necessary