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J Neuroinflamm 15:199 Ye K, Chen Z, Xu Y (2023) The double-edged functions of necroptosis

A 1% concentration is considered a strong dose

In addition, there are various other extraction strategies, like Immunoaffinity capture, ultra-filtering or size-exclusion chromatography (SEC), co-precipitation methods, and microfluidic advancements, that have been effectively utilized in the case of mammalian EXOs (Le Gall et al., 2020)