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The Fc domain can be changed to bind a different cell surface receptor (e.g., changed to bind a B cell FcR when the wild type Fc bound to a macrophage FcR or a mast cell FcR), an additional receptor (added function) or fewer receptors (loss of function)

TMZ is available in oral and injectable forms and works by inducing genomic DNA alkylation at the N 7 and O 6 positions of guanine and the N 3 position of adenine, resulting in nucleotide mismatch and death of tumor cells (Strobel et al

Exposure to extremely high altitudes (e.g., 7,000 m, ~9.8% O 2 ), as modeled in this study (Burtscher et al., 2018

According to the SDS-PAGE, though the release of Gln-Nb RNF43 needs at least 20 hs incubation, the release of Cys-15 Pd2,6ST was almost achieved within 8 h

Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats

[DOI] [PMC free article] [PubMed] [Google Scholar] Van Veldhoven P.P