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Understanding this cascade explains both why the peptide shows promise and why results vary so dramatically between individuals

A similar shift of 6 mV has also been reported for GRX1-roGFP1-iE (Birk et al., E of roGFP probes might be a mechanical strain that acts on the GFP barrel slightly affecting the thermodynamic stability of the disulfide

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This systematic review raises important questions about whether persistent symptoms in some patients may reflect ongoing biological mechanisms, including the possibility that persistent infection contributes in selected cases

doi: 10.1016/j.drudis.2021.02.008

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